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. 2012 May 1;5(3):294–296. doi: 10.4161/cib.19892

graphic file with name cib-5-294-g3.jpg

Figure 3. Model for PtdIns(3,4,5)P3-binding myosin I. PtdIns(3,4,5)P3 recruits myosin I to the plasma membrane of the leading edge and activates actin polymerization during chemotaxis and phagocytosis.