Table 5.
Sensitivity, Specificity, Positive and Negative Predictive Values and area under the receiver operating characteristic curve (AUC) of CMR Indices for the Detection of PH
Sensitivity | Specificity | PPV | NPV | AUC | |
---|---|---|---|---|---|
Cardiac morphology | |||||
RVEDV index ≥ 75 ml/m2 |
67 |
50 |
89 |
20 |
0.72* |
RV mass index ≥ 20 g/m2 |
83 |
84 |
96 |
50 |
0.91* |
VMI ≥ 0.4 |
81 |
88 |
97 |
50 |
0.91* |
Late gadolinium enhancement |
83 |
94 |
98 |
58 |
0.89* |
Right heart functional indices | |||||
RVEF ≤ 35% |
67 |
71 |
93 |
28 |
0.72* |
RVSVI ≤ 30 ml/m2 |
70 |
47 |
89 |
21 |
0.68* |
TAPSE ≤ 2 cm |
76 |
64 |
92 |
32 |
0.75* |
f-TAAD ≤ 25% |
88 |
56 |
92 |
44 |
0.78* |
SFD ≤ 1 cm |
77 |
67 |
93 |
34 |
0.73* |
f-SFD ≤ 25% |
79 |
64 |
92 |
35 |
0.78* |
RVRAC ≤ 30% |
61 |
81 |
95 |
28 |
0.79* |
sEI ≥ 1.2 |
65 |
61 |
90 |
24 |
0.72* |
dEI ≥ 1.17 |
62 |
54 |
88 |
20 |
0.57 |
Phase contrast CMR | |||||
Average velocity ≤ 10 (cm/s) |
82 |
62 |
94 |
32 |
0.80* |
Retrograde flow ≥ 0.3 (L/min/m2) |
83 |
71 |
95 |
38 |
0.84* |
Retrograde flow (%) |
73 |
56 |
87 |
34 |
0.75* |
PA relative area change ≥ 15% |
86 |
70 |
94 |
48 |
0.87* |
Systolic PA area ≥ 8 cm2 |
74 |
67 |
92 |
32 |
0.77* |
Diastolic PA area ≥ 6 cm2 | 88 | 66 | 94 | 52 | 0.82* |
AUC (area under the curve) *p < 0.05.