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. 2012 Aug 14;7(8):e43244. doi: 10.1371/journal.pone.0043244

Figure 3. Plasma Olanzapine levels after intragastric (IG) and intracerebroventricular (ICV) infusion of Olanzapine.

Figure 3

(IG: Vehicle group n = 5, Olanzapine group n = 6 and ICV Vehicle group n = 8 and Olanzapine group n = 12) Plasma Olanzapine levels are significantly higher in IG-Olanzapine-treated than in IG-vehicle-infused animals (One-Way ANOVA, p<0.001), or ICV-Olanzapine animals (2-Way ANOVA, Administration route * Treatment p<0.001). Plasma Olanzapine levels of ICV-Olanzapine animals are not significantly different from the ICV-Vehicle animals (One-Way ANOVA, p = 0.2). Vehicle-treated animals  =  white bars; Olanzapine-treated animals  =  black bars; *p<0.001.