Table 4. Meta-analysis of neonatal mortality outcomes by birth weight, gestational age, weight for gestational age, and stratified by weight for gestational age.
Outcome | Live Births | Deaths | Mortality Ratea | 95% CI | ORb | Distribution of Births | Distribution of Deaths | Attributable Risk Percentc | |
OR | 95% CI | ||||||||
All | 4,843 | 87 | 18.0 | 14.2–21.7 | — | — | 100% | 100% | — |
Birth weight | |||||||||
≥2,500 g | 4,398 | 51 | 11.6 | 8.4–14.8 | Ref | — | 90.9 | 58.6 | Ref |
<2,500 g | 445 | 36 | 80.9 | 55.4–106.3 | 7.6 | 4.80–12.2 | 9.2 | 41.3 | 85.7 |
Gestational age | |||||||||
≥37 wk | 4,649 | 60 | 12.9 | 9.7–16.1 | Ref | — | 96.1 | 68.9 | Ref |
34–36 wk | 156 | 9 | 57.7 | 20.7–94.7 | 6.2 | 3.0–12.8 | 3.2 | 10.3 | 77.6 |
<34 wk | 38 | 18 | 473.6 | 307.3–640 | 58.7 | 28.4–121.4 | 0.8 | 20.7 | 97.3 |
Weight for gestational age | |||||||||
Appropriate for gestational age | 3,854 | 57 | 15.0 | 11.0–18.6 | Ref | — | 79.6 | 66.3 | Ref |
Small for gestational age | 989 | 29 | 29.3 | 18.8–39.9 | 2.1 | 1.3–3.5 | 20.5 | 33.7 | 49.5 |
Stratified by weight for gestational age | |||||||||
Appropriate for gestational age | |||||||||
≥37 wk | 3,718 | 42 | 11.0 | 7.7–14.4 | Ref | — | 76.7 | 48.3 | Ref |
34–36 wk | 106 | 2 | 18.8 | −7.3 to 44.3 | 3.18 | 1.0–10.7 | 2.2 | 2.3 | 41.5 |
<34 wk | 30 | 14 | 466.7 | 277.2–656.1 | 74.9 | 32.6–171.7 | 0.6 | 16.1 | 97.6 |
Small for gestational age | |||||||||
≥37 wk | 934 | 19 | 20.3 | 11.3–29.4 | 2.23 | 1.2–4.10 | 19.3 | 21.8 | 45.8 |
34–36 wk | 48 | 7 | 145.8 | 42.2–249.4 | 19.88 | 8.3–47.5 | 1.0 | 8.0 | 92.5 |
<34 wk | 7 | 3 | 428.6 | −65.8 to 922.9 | 56.97 | 11.1–291.7 | 0.1 | 3.4 | 97.4 |
NRM expressed per 1,000 live births.
Calculated from fixed effects meta-analysis, using Mantel-Haenszel methods for pooled ORs.
Attributable risk percent calculated as the observed mortality that could be attributed to different weight for gestational age outcomes.