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. 2012 Aug 14;6(8):e1775. doi: 10.1371/journal.pntd.0001775

Table 2. Results of the included case-control studies on the association between toxocariasis and epilepsy.

References PWE, n PWOE, n Seropositivity in PWE, n (%) Seropositivity in PWOE, n (%) A priori statistical power, %* A posteriori statistical power, % OR (95% CI) p-value
Glickman et al., J Pediatr 1979 [30] 84 108 19 (22.6) 11 (10.2) 33.6 65.3 2.58 (1.15–5.77) 0.018
Arpino et al., Epilepsia 1990 [31] 91 214 20 (21.9) 26 (12.1) 40.1 59.3 2.04 (1.07–3.88) 0.028
Nicoletti et al., Neurology 2002 [35] 113 233 28 (24.8) 28 (12.0) 47.6 85.0 2.41 (1.35–4.31) 0.002
Akyol et al., Seizure 2007 [41] 100 50 12 (12.0) 4 (8.0) 32.8 11.3 1.57 (0.48–5.14) 0.4
Nicoletti et al., Epilepsia 2007 [36] 191 191 114 (59.7) 97 (50.8) 90.9 41.0 1.43 (0.96–2.15) 0.08
Nicoletti et al., Epilepsia 2008 [37] 231 201 38 (16.4) 13 (6.5) 55.8 89.6 2.85 (1.47–5.51) 0.001
Winkler et al., Trans R Soc Trop Med Hyg. 2008 [38] 40 20 19 (47.5) 8 (40.0) 33.5 8.0 1.36 (0.46–4.03) 0.58
*

Statistical power assuming an odds ratio equal to 2 with a type I error equal to 5% and one control per case.

OR, crude odds ratio; PWE, people with epilepsy as cases; PWOE, people without epilepsy as controls; seropositivity, presence of antibodies anti-Toxocara spp.; 95% CI, 95% confidence interval.