Figure 1. Tubercidin-loaded erythrocytes are toxic to E. histolytica.

Trophozoites were exposed to tubercidin-loaded erythrocytes two or three times (# of Treatments) and viability was assessed 24 hours or 48 hours after treatment. The data are reported as a percent of the starting number of viable amoebae before treatment. The data represent the mean ± S.D of ≥3 trials (***P<0.001). Three treatments of E. histolytica cells with tubercidin-charged hRBCs resulted in the death of nearly 100% of the cells 48 hours after application of selection.