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. 2012 Aug 14;7(8):e43025. doi: 10.1371/journal.pone.0043025

Figure 6. Cycloheximide is toxic to E. histolytica cells over-expressing H644 or EhLimA.

Figure 6

Transgenic trophozoites were exposed to 100 nM cycloheximide for 48 hours after which viability was assessed. The data are reported as a percent of untreated control amoebae. The data represent the mean ± S.D of 3 trials. Cycloheximide was toxic to both untransfected wild-type (WT) amoebae and E. histolytica transgenic cells. Therefore, cells over-expressing H644 or EhLimA do not exhibit a multidrug resistance phenotype.