Table 2.
Univariate and multivariate Cox proportional hazard regression analyses of OS in the VMP cohort (n=117)
Univariate |
Multivariate |
|||
---|---|---|---|---|
HR (95% CI) | p Value | HR (95% CI) | p Value | |
Gender (M or F) | 0.68 (0.34 to 1.38) | 0.29 | 1.07 (0.43 to 2.61) | 0.88 |
Age (>70) | 1.44 (0.97 to 2.9) | 0.3 | 1.68 (0.72 to 3.9) | 0.22 |
AJCC stage (I, II, III, IV) | 3.6 (2.24 to 5.79) | 1.16 × 10–7 | 2.9 (1.82 to 4.93) | 1.59 × 10–5 |
Grade (1, 2, 3) | 1.72 (0.8 to 3.69) | 0.16 | 2.31 (1.03 to 5.2) | 0.04 |
Gene signature (A or B) | 2.1 (1.0 to 4.3) | 0.036 | 3.08 (1.33 to 7.14) | 0.008 |
AJCC, American Joint Committee on Cancer; F, female; M, male; OS, overall survival; VMP, Vanderbilt and Max Planck.