Figure 4.
Group data demonstrating the negative regulation of evoked NAc activity by PFC subregions. Neurons recorded in the lateral NAc (A) were primarily activated by the OFC and in these neurons a preceding input from the mPFC significantly attenuates OFC-evoked responses (* represents significant difference from OFC activation alone: p<0.05, 1-way ANOVA; n = 12). Similarly, in medial NAc neurons activated by mPFC stimulation (B), the preceding activation of OFC afferents significantly inhibited evoked activity (* represents significant difference from mPFC activation alone: p<0.05, 1-way ANOVA; n = 13).