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Effect of Gd2O3 incubation concentration on MR relaxation times and cell function.
| Incubation medium [Gd] (mM) | Measured MR relaxation times | Cell function assays | ||
|---|---|---|---|---|
| T 1 (ms) | T 2 (ms) | Viability (%) | Proliferation (%) | |
| 0 | 2168 ± 161 | 83.5 ± 10.3 | 100 ± 9 | 100 ± 16 |
| 0.002 | 1920 ± 187 | 69.4 ± 10.5 | 105 ± 14 | 104 ± 21 |
| 0.02 | 1650 ± 224 | 50.3 ± 9.1 | 112 ± 18 | 81 ± 9 |
| 0.1 | 950 ± 137 | 15.4 ± 3.6 | 95 ± 21 | 76 ± 13 |
| 0.2 | 630 ± 91 | 12.6 ± 2.7 | 84 ± 3 | 61 ± 5∗ |
∗ P < 0.05, significantly different from control (0 mM).
