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Effect of SPIO incubation concentration on MR relaxation times and cell function.
| Incubation medium [Fe] (mM) | Measured MR relaxation times | Cell function assays | ||
|---|---|---|---|---|
| T 1 (ms) | T 2 (ms) | Viability (%) | Proliferation (%) | |
| 0 | 2166 ± 135 | 85.7 ± 9.0 | 100 ± 14 | 100 ± 18 |
| 0.0036 | 1263 ± 193 | 16.1 ± 2.6 | 96 ± 19 | 92 ± 8 |
| 0.009 | 828 ± 127 | 12.6 ± 0.6 | 96 ± 15 | 96 ± 19 |
| 0.018 | 613 ± 65 | 11.3 ± 0.6 | 95 ± 13 | 89 ± 12 |
| 0.036 | 630 ± 60 | 10.9 ± 0.5 | 86 ± 16 | 84 ± 15 |
