Table 3.

Effect of MEPG and VAD isolated from fruit rinds of Punica granatum on protein tyrosine phosphatase-1B (PTP1B) enzyme activity in in vitro.

Sl. no	Sample	Concentration (μg/mL)	% Inhibition#	IC50 (μg/mL)∗
		5	21.6 ± 0.24
		10	39.6 ± 0.15
(1)	Methanolic extract	25	55.4 ± 0.22	26.25
		50	78.7 ± 0.34
		100	98.9 ± 0.22
		5	33.3 ± 0.35
		10	46.7 ± 0.54
(2)	Valoneic acid dilactone	25	68.5 ± 0.64	12.41
		50	84.0 ± 0.11
		100	98.5 ± 0.75

Values are expressed as mean ± SEM (% inhibition^#) and mean (IC₅₀*) of three trials.