Table 6.

Sensitivity and specificity of the six diagnostic tests according to each level of the three covariates obtained with model ModII (L = 6, M = 3, V = 2).

		Sensitivity			Specificity
Test	Covariates	Mean	P2.5%	P97.5%	Mean	P2.5%	P97.5%
ELISA	General	0.9925	0.9537	0.9998	0.9589	0.8577	0.9940
	AGE- ≤ 30 years	0.9877	0.9261	0.9998	0.9919	0.9614	0.9993
	AGE- > 30 years	0.9953	0.9704	0.9999	0.7952	0.5007	0.9647
	GEN-male	0.9876	0.9255	0.9998	0.9941	0.9771	0.9994
	GEN-female	0.9953	0.9707	0.9999	0.7604	0.3585	0.9609
	RFE-no	0.9878	0.9252	0.9998	0.9941	0.9740	0.9994
	RFE-yes	0.9952	0.9713	0.9999	0.7592	0.3625	0.9566
IIF	General	0.9913	0.9472	0.9999	0.9936	0.9529	0.9999
	AGE- ≤ 30 years	0.9856	0.9112	0.9998	0.9987	0.9928	1
	AGE- > 30 years	0.9945	0.9677	0.9999	0.9605	0.7202	0.9996
	GEN-male	0.9860	0.9128	0.9998	0.9991	0.9940	1
	GEN-female	0.9943	0.9650	0.9999	0.9559	0.6674	0.9996
	RFE-no	0.9856	0.9171	0.9998	0.9991	0.9937	1
	RFE-yes	0.9945	0.9650	0.9999	0.9561	0.6845	0.9996
IHA	General	0.9912	0.9406	0.9998	0.9930	0.9468	1
	AGE- ≤ 30 years	0.9852	0.9038	0.9997	0.9988	0.9924	1
	AGE- > 30 years	0.9945	0.9667	0.9999	0.9588	0.7063	0.9997
	GEN-male	0.9858	0.9087	0.9997	0.9990	0.9932	1
	GEN-female	0.9943	0.9638	0.9999	0.9570	0.6813	0.9997
	RFE-no	0.9855	0.8989	0.9997	0.9990	0.9920	1
	RFE-yes	0.9945	0.9619	0.9999	0.9560	0.6992	0.9997
HEMO	General	0.3782	0.3140	0.4442	1	1	1
	AGE- ≤ 30 years	0.2959	0.1936	0.4110	1	1	1
	AGE- > 30 years	0.4715	0.3537	0.6006	1	1	1
	GEN-male	0.4014	0.3328	0.4677	1	1	1
	GEN-female	0.4467	0.3511	0.5396	1	1	1
	RFE-no	0.3116	0.2077	0.4275	1	1	1
	RFE-yes	0.4526	0.3317	0.5823	1	1	1
c-ELISA	General	0.9911	0.9461	0.9998	0.8703	0.7333	0.9513
	AGE- ≤ 30 years	0.9853	0.9055	0.9997	0.9747	0.9179	0.9951
	AGE- > 30 years	0.9944	0.9630	0.9999	0.5181	0.2540	0.8044
	GEN-male	0.9861	0.9189	0.9997	0.9795	0.9360	0.9954
	GEN-female	0.9941	0.9625	0.9999	0.4744	0.1936	0.7790
	RFE-no	0.9858	0.9175	0.9997	0.9791	0.9345	0.9955
	RFE-yes	0.9942	0.9605	0.9999	0.4805	0.1946	0.7862
rec-ELISA	General	0.9908	0.9435	0.9998	0.9941	0.9591	1
	AGE- ≤ 30 years	0.9886	0.9294	0.9998	0.9990	0.9939	1
	AGE- > 30 years	0.9923	0.9558	0.9999	0.9606	0.7286	0.9996
	GEN-male	0.9848	0.9129	0.9997	0.9991	0.9940	1
	GEN-female	0.9942	0.9659	0.9999	0.9588	0.6933	0.9997
	RFE-no	0.9851	0.9073	0.9997	0.9992	0.9944	1
	RFE-yes	0.9941	0.9646	0.9999	0.9590	0.7259	0.9997

P2.5%: 2.5th percentile; P97.5%: 97.5th percentile; ELISA: enzyme-linked immunosorbent assay; IIF: indirect immunofluorescence; IHA: indirect hemagglutination; HEMO: blood culture; c-ELISA: conventional ELISA using the Biomanguinhos kit; rec-ELISA (recombinant ELISA using the Biomanguinhos kit and CRA and FRA antigens); AGE-age (≤30, >30 years); GEN-gender (male, female); RFE-presence of at least two of three risk factors epidemiological (origin from an endemic region, contact with the vector transmitting the disease, and family history of Chagas' disease).