Skip to main content
. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: Multiscale Model Simul. 2011 Nov 17;9(4):1420–1443. doi: 10.1137/100815335

Figure 9.

Figure 9

Mechanical and chemical model combined. Forces on the “front” edge are determined by the reaction-diffusion system inside the evolving, moving cell domain. Top: A time sequence of cell shapes and positions, from t = 0s to t = 800s at intervals of 100s starting from the circle at the left. The distance scale is in cm (10−4cm = 1 μm). Bottom: Sample shots of the same moving cell at intervals of 200s showing the internal chemical distribution. The cell is initially disk-shaped, with homogeneous internal concentrations of a, b. At t = 0 a stimulus (biased towards the right) leads to chemical polarization. RD equations (7–9) were solved in the domain Ωc using parameter values as in Fig. 8. The RD system very rapidly polarizes and maintains the polarization of the cell. There is a slight change in the cell’s direction of travel over long times.