Table 2.
Significant differences in mRNA expression between kidney cortex and the RCC types
| All RCC combined* | ccRCC* | pRCC* | chRCC* | Altered expression | Difference RCC types† | |
|---|---|---|---|---|---|---|
| EGFR |
< 0.001 |
0.001 |
0.016 |
NS |
Up-regulation |
NS |
| ErbB2 |
0.003 |
0.001 |
NS |
NS |
Down-regulation |
< 0.001 |
| ErbB3 |
NS |
NS |
NS |
NS |
- |
NS |
| ErbB4 |
0.001 |
< 0.001 |
0.001 |
0.03 |
Down-regulation |
NS |
| LRIG1 | NS | 0.015 | NS | NS | Down-regulation | 0.002 |
* P-values were calculated in comparison to kidney cortex using the Mann–Whitney U-test.
† Comparison of the significant differences between the RCC types was performed using the Kruskal-Wallis test.
NS, non-significant.