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. 2012 Aug 15;7(8):e43521. doi: 10.1371/journal.pone.0043521

Figure 4. PMA promoted the loss of adhesion in Matrigel™ in HaCaT cells and SCC-9 cells.

Figure 4

Adhesion assay showed that the cells stimulated by PMA decreased the ability to adhere to extracellular matrix proteins. HaCaT (A) and SCC-9 (B) cells had the ability to adhere in Matrigel™ diminished after 24 h of PMA treatment. Three independent experiments were performed with triplicates. Columns represent mean ± SD (n = 3) and * indicates p<0.01, normalized with the control (vehicle: DMSO). (C) Representative micrographs (magnification 40×) of adherent cells after PMA and vehicle (DMSO) treatments.