Figure 7. Effect of compound 8 on the invasion of LM8G7 cells.

Cells (2.5×10⁴) were seeded in Matrigel™-coated Boyden chambers and were incubated for 24 h with DMEM (A) or a medium containing 0.5 µM of compound 8 (B) or 1 µM compound 8 (C); the photographs (100×) shows the cell on the lower surface of the filter (invaded) stained with the Diff-Quick solution. (D) Inhibition rate of the compound 8 on LM8G7 invasion was presented as described under “Experimental Procedures”. Bars represent the mean ± SD of three independent experiments. * P<0.05 versus control. ** P<0.01 versus control.