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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Epilepsy Res. 2012 May 9;101(3):268–276. doi: 10.1016/j.eplepsyres.2012.04.014

Figure 5.

Figure 5

SE induced by peripheral injection of DFP and response to diazepam treatment. Samples of recording from an animal in SE show continuous electrographic seizures for 4 hours. Recordings an animal treated with diazepam 10 minutes after the onset of continuous electrographic seizures (Middle panel, 10 minute treatment) demonstrate prompt termination of SE.. When diazepam was administered 30 minutes after the onset of continuous electrographic seizures (Right panel 30 minute treatment) SE continued with only a mild suppression of amplitude of spikes but continued high frequency spike-wave discharges (1 hour) and complex poly-spike-wave rhythmic discharges (4 hour).