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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2012 May 4;7(3):591–598. doi: 10.1007/s11481-012-9361-4

Fig. 5.

Fig. 5

LPI injection increased serum IgE. Lysophosphatidylinositol (LPI), a ligand for GPR55, pretreatment of BALB/c mice enhanced the serum levels of total IgE. The mice were pre-treated with either cannabidiol (CBD) or SR141716A (SR1) prior to LPI followed by sensitization of OVA/ALUM following a boost of same antigen. Treatment with either CBD or SR1 only had no effect on IgE levels (data not shown). The sera were collected at Day 6 after the boost and ELISAs were performed. Data bars represent serum from 4–14 mice/group +/− SEM. *=p≤0.05 vs Normal; **=p≤0.05 vs OVA/ALUM