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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Bioorg Med Chem. 2012 Jul 6;20(17):5247–5253. doi: 10.1016/j.bmc.2012.06.046

Table 1.

One-pot synthesis of 1-(thiazol-5-yl)-2-(1H-1,2,3-triazol-1-yl)ethanones 3a–i.

graphic file with name nihms392664u1.jpg
entry compound R yield
1 3a -Ph 85%
2 3b -CH2OH 76%
3 3c -CH2OCH3 73%
4 3d -CH2N(CH3)2 56%
5 3e -(CH2)3CN 68%
6 3f -CH2N(CH2CH2)O* 74%
7 3g -COOCH3 52%
8 3h -4-Cl-Ph 95%
9 3i -CH2CH2OH 70%
*

morpholine