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. 2012 Aug;15(4):395–404. doi: 10.1089/rej.2011.1302

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Copyright 2012, Mary Ann Liebert, Inc.

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FIG. 1. — Quantile–quantile (Q-Q) plots for gene expression analysis of Mini-Mental State Examination (MMSE) score at RNA collection. (A) The Q-Q plot for the genome-wide analysis of MMSE at RNA collection is shown. The actual p values (−log₁₀) obtained are given on the y axis, plotted against expected p values (−log₁₀) given on the x axis. This graph shows potential deviations to the p value distribution that might be expected by chance. (B) The Q-Q plot for the focused analysis of inflammatory genes is shown. The actual p values (−log₁₀) obtained are given on the y axis, plotted against expected p values (−log₁₀) given on the x axis. This graph shows potential deviations to the p value distribution that might be expected by chance. The positive association with the CCR2 transcript is evident in both plots.