FIG. 1.
The effect of oxygen tension during expansion and differentiation on chondrogenesis of infrapatellar fat pad–derived stem cells (FPSCs) in pellet culture for 21 days. Pellet morphology (A), DNA content (B), sulfated glycosaminoglycan (sGAG) and collagen content (C), and GAG/DNA and collagen/DNA (D). Scale bar, 1 mm. “*” indicates a significant difference between FPSCs undergoing chondrogenesis at either 5% or 20% O2, where all other culture conditions during differentiation were identical. “a” indicates a significant difference between FPSCs expanded at either 20% or 5% O2, where all other culture conditions during differentiation were identical. Color images available online at www.liebertonline.com/tea