FIG. 6.

Effects of hypoxia on vessel morphology and pericyte coverage. The vessels in hypoxia were significantly wider than in normoxia (A, D), while lengths were similar (C). In addition, in hypoxia, there were significantly less αSMA+ cells surrounding vessels (B) and throughout the culture (E). (F) mRNA expression of endothelial markers was higher in hypoxia than in normoxia by day 14, while expression of αSMA was less in hypoxia at day 7. Significance indicated as *p<0.05, **p<0.01, or ***p<0.001 versus normoxia. Scale bars=10 μm (A) and 100 μm (B). Color images available online at www.liebertonline.com/tea