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. 2012 May 9;18(15-16):1729–1740. doi: 10.1089/ten.tea.2011.0599

FIG. 8.

FIG. 8.

Schematic of the heterotypic interactions that mediate ASC vascular assembly. The top row depicts the growth and assembly of the vascular structures over time, with αSMA+ cells being recruited by PDGF-B secreted by the growing vessels. The bottom row is an interpretation of the evolution of these structures from a two-dimensional monolayer into a complex, three-dimensional structure. The recruitment of the supportive cells drives migration and multilayered, cell-on-cell clustering around the vessel. Color images available online at www.liebertonline.com/tea