FIG. 1.

Adipose-derived mesenchymal stromal cells (adMSC) Cotransplantation drives HMEC vessel-like structure formation surrounding modules. Photographs of human microvascular endothelial cells (HMEC)+adMSC modular implants appear red, with blood vessels visible throughout the module clump at day 3, 7, and 14 (A). UEA-1 lectin staining (B) shows that the human-derived EC detach from the module surface to form vessel-like structures. These vessels appear to become larger and more organized at day 7 and 14. Higher magnification UEA-1 lectin images (C) show that these vessels contain erythrocytes suggesting anastomosis with the host. Arrows highlight some large UEA-1 stained vessels containing erythrocytes, with some modules highlighted by dashed lines. Scale bar=100 μm. Color images available online at www.liebertpub.com/tea