FIG. 3.

HMEC-derived vessels contain mouse erythrocytes. These vessels decrease in number but increase in size over 14 days with adMSC cotransplantation indicating vessel maturation. Hematoxylin and eosin (H&E) staining of micrographs of HMEC+adMSC modules shows vessels containing erythrocytes surrounding modules at day 3, 7, and 14. Corresponding serial sections stained with UEA-1 show that these vessels are of human origin (arrows highlight some vessels) (A). Microvessel density counts showed a large number of small vessels observed at early time points, while by day 14 the number of vessels has decreased and the average vessel diameter is larger (B). No HMEC vessels were counted for the HMEC-only case as this number was zero for all time points. Error bars represent±SD; n=9; * p<0.05. Color images available online at www.liebertpub.com/tea