Table 2. Gene Ontology Functional Enrichment Annotation of consensus TSLC network genes with different gene grouping according to the topological characteristics.

Gene grouping	GO Category	GO Term	%	P-Value
All genes	BP	GO:0006355~regulation of transcription, DNA-dependent	46%	1.8E-06
	BP	GO:0042981~regulation of apoptosis	27%	4.0E-08
	CC	GO:0031981~nuclear lumen	25%	2.9E-06
	BP	GO:0006325~establishment and/or maintenance of chromatin architecture	21%	3.2E-07
Inter-modular hubs	MF	GO:0005515~protein binding	100%	8.1E-05
	BP	GO:0043170~macromolecule metabolic process	83%	0.02
	BP	GO:0048731~system development	42%	0.03
	BP	GO:0006468~protein amino acid phosphorylation	33%	0.01
Intra-modular hubs	CC	GO:0043231~intracellular membrane-bound organelle	100%	1.3E-07
	BP	GO:0043170~macromolecule metabolic process	95%	6.4E-06
	BP	GO:0050794~regulation of cellular process	90%	1.8E-08
	BP	GO:0006355~regulation of transcription, DNA-dependent	71%	9.2E-08
	BP	GO:0006325~establishment and/or maintenance of chromatin architecture	43%	2.9E-09