Table 3. Correlation of BARD1 expression patterns with survival in 75 colorectal cancer patients.
1-year survival
|
2-year survival
|
3-year survival
|
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---|---|---|---|---|---|---|---|---|
Expression pattern | No. of patients | Median survival | % | P -value | % | P -value | % | P -value |
++++ vs −++− | 17 vs 31 | 27 vs 9 | 88.2 vs 41.9 | 0.0019 | 52.9 vs 16.1 | 0.0073 | 41.2 vs 6.5 | 0.0032 |
++++ vs −+++ | 17 vs 11 | 27 vs 12 | 88.2 vs 45.5 | 0.0144 | 52.9 vs 18.2 | 0.0659 | 41.2 vs 9.1 | 0.0664 |
++++ vs others | 17 vs 58 | 27 vs 12 | 88.2 vs 48.3 | 0.0034 | 52.9 vs 22.4 | 0.0151 | 41.2 vs 13.8 | 0.0131 |
−++− vs −+++ | 31 vs 11 | 9 vs 12 | 41.9 vs 45.5 | 0.8390 | 16.1 vs 18.2 | 0.8750 | 6.5 vs 9.1 | 0.7702 |
−++− vs others | 31 vs 44 | 9 vs 16.5 | 41.9 vs 68.2 | 0.0236 | 16.1 vs 38.6 | 0.0350 | 6.5 vs 29.5 | 0.0138 |
−+++ vs others | 11 vs 64 | 12 vs 15.5 | 45.5 vs 59.4 | 0.3885 | 18.2 vs 31.3 | 0.3792 | 9.1 vs 21.9 | 0.3274 |
Note: ++++, four antibodies positive staining; −++−, only PVC and WFS positive staining; −+++, only N19-negative staining; others, other than the expression pattern that is compared.