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. 2012 Jul 19;107(4):675–683. doi: 10.1038/bjc.2012.297

Table 3. Correlation of BARD1 expression patterns with survival in 75 colorectal cancer patients.

      1-year survival
2-year survival
3-year survival
Expression pattern No. of patients Median survival % P -value % P -value % P -value
++++ vs −++− 17 vs 31 27 vs 9 88.2 vs 41.9 0.0019 52.9 vs 16.1 0.0073 41.2 vs 6.5 0.0032
++++ vs −+++ 17 vs 11 27 vs 12 88.2 vs 45.5 0.0144 52.9 vs 18.2 0.0659 41.2 vs 9.1 0.0664
++++ vs others 17 vs 58 27 vs 12 88.2 vs 48.3 0.0034 52.9 vs 22.4 0.0151 41.2 vs 13.8 0.0131
−++− vs −+++ 31 vs 11 9 vs 12 41.9 vs 45.5 0.8390 16.1 vs 18.2 0.8750 6.5 vs 9.1 0.7702
−++− vs others 31 vs 44 9 vs 16.5 41.9 vs 68.2 0.0236 16.1 vs 38.6 0.0350 6.5 vs 29.5 0.0138
−+++ vs others 11 vs 64 12 vs 15.5 45.5 vs 59.4 0.3885 18.2 vs 31.3 0.3792 9.1 vs 21.9 0.3274

Note: ++++, four antibodies positive staining; −++−, only PVC and WFS positive staining; −+++, only N19-negative staining; others, other than the expression pattern that is compared.