Table 3. Univariate and multivariate analysis of disease-free survival.

Parameters	Risk ratio	95% CI	P -value
Univariate analysis
Age
⩽65	1
>65	0.7672	0.4227–1.3998	0.3839
Gender
Male	1
Female	0.8843	0.4873–1.6304	0.6885
Site
Tongue	1
Other	0.9075	0.4927–1.6449	0.750
Histology
Well	1
Mod/Poor	2.4833	1.3989–4.7785	0.0022
T classification
T1-T2	1
T3-T4	1.4582	0.7206–2.759	0.2805
Clinical stage
I, II	1
III, IV	2.6417	1.4539–4.8528	0.0015
Nodal metastasis
Negative	1
Positive	4.7203	2.5653–8.7999	<0.0001
MVD
Low	1
High	1.0094	0.9827–1.0357	0.4872
LVD
Low	1
High	0.8492	0.4444–1.5712	0.607
miR-126
High	1
Low	4.0492	1.7558–11.0409	0.0006
Multivariate analysis
Histology
Well	1
Mod, Poor	0.6673	0.3493–1.2557	0.2101
Clinical stage
I, II	1
III, IV	1.8972	0.9434–3.8782	0.0725
Nodal metastasis
Negative	1
Positive	2.6265	1.2658–5.6413	0.0093
miR-126
High	1
Low	2.631	0.9886–7.9851	0.048

Abbreviations: CI=confidence intervals; miR-126=microRNA-126; Mod=moderately differentiated squamous cell carcinoma; Poor=poorly differentiated squamous cell carcinoma; Well=well-differentiated squamous cell carcinoma.

The univariate analysis was performed by log-rank test, and the multivariate analysis was performed by the Cox proportional hazard model.