Figure 7.
Gelatin zymography demonstrating the activity of MMP-2 and MMP-9 in myocardial infarct tissue isolated from control and AdLDLr-treated female C57BL/6 LDLr−/− mice 3 days after MI. Pro-MMP-9 (a), pro-MMP-2 (b) and active MMP-2 (c) levels are expressed in arbitrary units relative to the pro-MMP-9 value in control female C57BL/6 LDLr−/− mice. Data are shown as means±s.e.m. (n=8 per group). (d) Representative zymogram gel showing gelatinolytic activity in the 3-day-old infarcts of both mice groups. A.U., arbitrary units.