. 2011 Oct 6;19(8):860–871. doi: 10.1038/gt.2011.147

Table 3. Histological analysis of remote LV myocardium in non-infarcted control C57BL/6 LDLr^−/− mice and in control and AdLDLr-treated female C57BL/6 LDLr^−/− mice 7 days and 28 days after MI.

	Non-infarcted	7 Days after MI		28 Days after MI
	Control (n=11)	Control (n=9)	AdLDLr (n=9)	Control (n=21)	AdLDLr (n=22)
Cardiomyocyte cross-sectional area (μm²)	220±21	200±6.4	170±9.0^*	250±9.4^###	210±6.8^**##
Cardiomyocyte density (number mm⁻²)	4600±340	3900±120	4600±210^**	3500±110^§	3900±92^*##
Capillary density (number mm⁻²)	6000±400	4400±220^§§	5600±320^*	5000±220^§	5700±170^*
Relative vascularity (μm⁻²)	0.0064±0.00053	0.0058±0.00030	0.0071±0.00042^*	0.0059±0.00027	0.0071±0.00026^**
Collagen deposition (% of total LV remote area)	1.9±0.084	4.0±0.17^§§§§	3.1±0.14^**§§§§	4.1±0.22^§§§§	3.3±0.20^*§§§
Leukocyte infiltration (number mm⁻²)	340±25	700±63^§§§	520±46^*§	410±23^##	420±51

Abbreviations: AdLDLr, adenoviral LDLr; MI, myocardial infarction; LDLr, LDL receptor; LV, left ventricular.

^*P<0.05,^**P<0.01 for comparison of control versus AdLDLr-treated mice.

^§P<0.05, ^§§P<0.01, ^§§§P<0.001, ^§§§§P<0.0001 for comparison versus non-infarcted mice.

^##P<0.01, ^###P<0.001 for comparison of day 7 versus day 28 after MI.

Data are expressed as means±s.e.m.

Table 3. Histological analysis of remote LV myocardium in non-infarcted control C57BL/6 LDLr−/− mice and in control and AdLDLr-treated female C57BL/6 LDLr−/− mice 7 days and 28 days after MI.