Table 1. Characteristics of 326 unrelated donor search activation.
Patients, N | 326 |
Median age, years (range) | 50 (15–66) |
Sex, M/F (%) | 193/133 (59/41) |
Diagnosis, N (%) | |
ALL | 5 (2) |
AML | 62 (19) |
CML | 11 (3) |
MDS | 20 (6) |
MMF | 10 (3) |
NHL | 73 (22) |
B-CLL | 34 (10) |
HD | 104 (32) |
MF/SS | 7 (2) |
MUD transplants performed, N (%) | 121 (37) |
Days from search activation to transplant, median (range) | 169 (68–772) |
Stopped searches, N (%) | 192 (59) |
Days from search activation to stop, median (range) | 270 (1–74 225) |
Reason for search interruption | |
Death of the patient | 100 (52) |
No longer eligible | 34 (18) |
Donor not available | 11 (6) |
Withdrawn consent | 8 (4) |
Another protocol | 39 (20) |
Autologous transplant | 1 |
Allogeneic transplant with cord blood | 3 |
Allogeneic transplant with related mismatch donor | 15 |
Allogeneic transplant with haploidentical donor | 2 |
Other unspecified treatments | 18 |
Ongoing searches, N (%) | 13 (4) |
Days from search activation to last visit, median (range) | 2220 (1305–2691) |
Abbreviations: ALL, acute lymphoid leukemia; AML, acute myeloid leukemia; B-CLL, B-cell chronic lymphocytic leukemia; CML, chronic myeloid leukemia; F, female; HD, Hodgkin's disease; M, male; MDS, myelodysplastic Syndrome; MF, mycosis fungoides; MMF, myelofibrosis; MUD, marrow unrelated donor; NHL, non-Hodgkin's lymphoma; SS, Sezary's syndrome.