Histological Characterization of the Testes of Mice Treated with JQ1 or Control, Related to Figure 6
(A and B) Immunohistochemical study (20x) of ZPBP1 in seminiferous tubules of male mice treated daily from 6-12 weeks with vehicle control (A) or JQ1 (B).
(C and D) Immunohistochemical study (20x) of TNP2 in testis tubules of male mice treated BID from 9-12 weeks with vehicle control (C) or JQ1 (D).
(E–H) Immunofluorescence study (40x) of GASZ in testis tubules of male mice treated BID from 9-12 weeks with vehicle control (E, G) or JQ1 (F, H). GASZ is expressed in nuage granules in pachytene spermatocytes.