Table 1a. Demographics and baseline characteristics of stratum 1 patients.

Parameter	PF-04523655 (μg)									Total
	50	100	200	400	670	1000	1500	2250	3000
	(N=3)	(N=3)	(N=3)	(N=3)	(N=3)	(N=3)	(N=3)	(N=3)	(N=3)	(N=27)
Age (years)
Mean	88.3	77.7	78.3	79.0	75.3	76.3	80.3	77.3	79.3	79.1
SD	4.16	7.57	6.66	7.00	6.81	6.35	4.16	7.51	7.09	6.51
Median	87.0	81.0	80.0	82.0	73.0	80.0	79.0	73.0	78.0	80.0
Min, max	85, 93	69, 83	71, 84	71, 84	70, 83	69, 80	77, 85	73, 86	73, 87	69, 93
Gender, n (%)
Male	1 (33.3)	0 (0)	0 (0)	2 (66.7)	1 (33.3)	3 (100)	1 (33.3)	1 (33.3)	1 (33.3)	10 (37.0)
Female	2 (66.7)	3 (100)	3 (100)	1 (33.3)	2 (66.7)	0 (0)	2 (66.7)	2 (66.7)	2 (66.7)	17 (63.0)
Race, n (%)
White	3 (100)	3 (100)	3 (100)	3 (100)	3 (100)	3 (100)	3 (100)	3 (100)	3 (100)	27 (100)
BCVA (letters)
n	3	3	3	3	3	3	3	3	3	27
Mean	21.7	26.0	25.7	15.7	14.7	31.3	15.3	19.0	6.3	19.5
SD	12.74	10.15	4.16	14.19	10.02	3.21	13.20	6.00	2.08	10.71
Median	28.0	24.0	27.0	13.0	14.0	30.0	18.0	19.0	7.0	21.0
Min, max	7, 30	17, 37	21, 29	3, 31	5, 25	29, 35	1, 27	13, 25	4, 8	1, 37
CRT (μm)
n	3	3	3	3	2	3	2	2	3	24
Mean	401.2	794.5	523.8	564.8	914.8	571.2	482.5	1646.3	1111.3	749.5
SD	42.95	52.43	206.96	148.23	624.73	237.55	81.32	121.98	668.78	441.19
Median	415.0	771.5	415.0	589.0	914.8	506.0	482.5	1646.3	967.0	564.5
Min, max	353, 436	758, 855	394, 763	406, 700	473, 1357	373, 835	425, 540	1560, 1733	527, 1841	353, 1841

Abbreviations: BCVA, best corrected visual acuity; CRT, central retinal thickness.