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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Lancet Infect Dis. 2012 Mar 19;12(6):441–448. doi: 10.1016/S1473-3099(12)70037-3

Table 3.

Rate and Hazard Ratio for ART eligibility

N Events/pyr Rate/100pyr Crude HR (95%CI) Adjusted HR (95%CI)
Overall 438 205/ 631.98 32.4
Study arm
Placebo 219 110/303.8 36.21 1.0 1.0
Treatment 219 95/328.1 28.95 0.79(0.60, 1.04) 0.75 (0.57,0.99)
Sex
Female 310 143/440.4 32.5 1.0 1.0
Male 128 62/191.6 32.4 0.98 (0.73,1.33) 0.79 (0.57,1.08)
Age-group
20-29 90 49/126.2 38.8 1.0 1.0
30-39 185 82/267.1 30.7 0.80 (0.56,1.14) 0.87 (0.60,1.24)
40-49 107 49/162.3 30.2 0.78 (0.53,1.16) 0.95 (0.63,1.44)
50+ 56 25/76.3 32.7 0.90 (0.56,1.46) 1.01 (0.62,1.67)
Baseline CD4
300-349 211 117/282.3 25.2 1.0 1.0
350-399 227 88/349.7 41.4 0.57 (0.43,0.75) 0.58 (0.44,0.77)
Baseline Viral load
<10 000 132 37/218.8 16.9 1.0
10 000-49 999 138 73/202.1 36.1 2.25 (1.51,3.34) 2.20 (1.47,3.29)
50 000-99 999 43 27/61.1 44.2 2.92 (1.77,4.79) 2.82 (1.70,4.68)
100 000+ 125 68/149.97 45.3 3.01 (2.02,4.50) 3.17 (2.10,4.78)
Baseline Viral load
<50 000 270 110/420.9 26.1 1.0
50 000+ 168 95/211.1 45.0 1.88 (1.43,2.48)

ART: antiretroviral therapy, pyr: person years, HR: hazard ratio