Quantitative analyses of fiber diameter (A), fractional area (B) and mean gray intensity (C) from endomicroscope images. Features were measured in NP, gestation days 6, 12, 15, and 18 mouse cervical sections. n = 3 animals per time point and 25–30 images per animal. All features progressively increased throughout pregnancy. Error bars represent a standard error mean (P < 0.0001 for all time points when comparing any two adjacent time points). All time points are significant from one another.