Table 3.
Critical components of the fluid challenge and one example of their application in a hypothetical patient (MAP of 65 mmHg and a CVP of 12 mmHg; two possible types of response are presented) [63].
| Example | example 1 | example 2 | ||||
|---|---|---|---|---|---|---|
| (1) Type of fluid: Ringer's lactate | Baseline | +10 mins | +20 mins | Baseline | +10 mins | +20 mins |
| (2) Rate of infusion: 500 mL/30 mins | ||||||
| (3) Clinical end-points: MAP of 75 mmHg | MAP 65 | MAP 70 | MAP 75 | MAP 65 | MAP 67 | MAP 60 |
| (4) Pressure safety limits: CVP of 15 mmHg | CVP 12 | CVP 13 Continue | CVP 14 Stop | CVP 12 | CVP 14 Continue | CVP 15 Stop |
| Successful fluid challenge | Unsuccessful fluid challenge | |||||
MAP: mean arterial pressure, CVP: central venous pressure, mins: minutes [63].