Table 3:

Concentrations of adenine nucleotides and lactate in myocardial biopsies obtained before aortic occlusion (I), after bolus cardioplegia (II), at 60 min of aortic occlusion (III) and at 20 min after release of aortic occlusion (IV)^a

		Adenosine group (n = 40)	Control group (n = 40)	P-valued
ATP (μmol g−1)	I	20.75 ± 2.87	20.42 ± 4.60	0.90
	II	20.85 ± 2.91	21.41 ± 4.10
	III	19.36 ± 3.21	19.66 ± 4.41
	IV	17.78 ± 3.52	17.01 ± 4.48
ADP (μmol g−1)	I	3.66 ± 1.51	3.66 ± 1.71	0.78
	II	3.44 ± 0.97	3.51 ± 1.40
	III	4.38 ± 1.60	4.24 ± 1.24
	IV	3.54 ± 1.30	3.39 ± 1.46
AMP (μmol g−1)	I	0.65 ± 0.55	0.86 ± 0.99	0.50
	II	0.55 ± 0.39	0.75 ± 0.85
	III	1.03 ± 0.95	1.01 ± 1.02
	IV	0.78 ± 0.64	0.79 ± 0.75
ATP/ADP	I	6.49 ± 2.51	6.66 ± 2.73	0.65
	II	6.52 ± 1.90	6.72 ± 2.04
	III	5.14 ± 2.26	5.15 ± 2.08
	IV	5.70 ± 2.28	5.91 ± 2.65
TANb (μmol g−1)	I	25.06 ± 2.63	24.93 ± 4.38	0.84
	II	24.85 ± 2.66	25.60 ± 4.37
	III	24.78 ± 2.35	24.92 ± 3.89
	IV	22.11 ± 3.13	21.19 ± 4.29
Energy charge (EC)c	I	0.90 ± 0.04	0.89 ± 0.07	0.55
	II	0.91 ± 0.04	0.90 ± 0.05
	III	0.87 ± 0.07	0.87 ± 0.06
	IV	0.88 ± 0.06	0.88 ± 0.07
Lactate (μmol g−1)	I	14.84 ± 6.72	14.75 ± 6.85	0.84
	II	26.29 ± 14.77	24.27 ± 13.93
	III	39.91 ± 20.68	39.46 ± 23.59
	IV	29.49 ± 24.93	30.91 ± 29.67

ADP, adenosine diphosphate; AMP, adenosine monophosphate; ATP, adenosine triphosphate; TAN, total adenine dinucleotide.

^aData are expressed as mean ± SD.

^bTAN = ATP + ADP + AMP.

^cEC = (ATP + ½ADP)/(ATP + ADP + AMP).

^dSignificance test of effect of treatment allocation in repeated-measures ANOVA.