Table 5.
Multivariate Cox regression analysis of survival
| |
Univariate |
Multivariate |
||||
|---|---|---|---|---|---|---|
| Characteristics | HR | 95% CI | P-value | HR | 95% CI | P-value |
|
Age, years |
|
|
|
|
|
|
| < 50 |
1 |
0.385 to 3.051 |
0.879 |
1 |
0.51 to 4.68 |
0.44 |
| 50 – 60 |
1.084 |
0.607 to 3.872 |
0.366 |
1.54 |
0.46 to 4.2 |
0.57 |
| 60 – 70 |
1.533 |
0.938 to 6.459 |
0.067 |
1.39 |
0.97 to 9.12 |
0.06 |
| > 70 |
2.462 |
|
|
2.98 |
|
|
|
Gender |
|
|
|
|
|
|
| Female |
1 |
0.499-2.008 |
0.998 |
1 |
0.39 to 2.25 |
0.88 |
| Male |
1.001 |
|
|
0.93 |
|
|
|
LNR |
|
|
|
|
|
|
| ≤ 0.4 |
1 |
1.472 to 6.234 |
0.003 |
1 |
1.25 to 22.12 |
0.02 |
| > 0.4 |
3.03 |
|
|
5.25 |
|
|
|
Stage |
|
|
|
|
|
|
| IIIA |
1 |
0.318 to 5.956 |
0.668 |
1 |
0.24 to 5.63 |
0.86 |
| IIIB |
1.377 |
0.836 to 17.67 |
0.084 |
1.15 |
0.21 to 14.64 |
0.60 |
| IIIC |
3.842 |
|
|
1.76 |
|
|
|
Positive LN |
|
|
|
|
|
|
| 1 – 3 |
1 |
0.993 to 4.185 |
0.052 |
1 |
0.12 to 2.08 |
0.35 |
| ≥ 4 |
2.039 |
|
|
0.51 |
|
|
|
Adj chemo |
|
|
|
|
|
|
| No |
1 |
0.279 to 1.235 |
0.16 |
1 |
0.21 to 1.27 |
0.15 |
| Yes | 0.586 | 0.52 | ||||
Adj chemo, adjuvant chemotherapy; LN, lymph node; LNR, lymph-node ratio.