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Acute locomotor responses to cocaine are similar in wild-type, D1-GFP, and D2-GFP mouse lines. A–C, Total distance traveled following intraperitoneal injection of saline (open symbols) or cocaine (filled symbols) in wild-type C57BL/6 (n = 12 saline and 12 cocaine), D1-GFP+/− mice (n = 4 saline and n = 23 cocaine), D2-GFP+/− mice (n = 6 saline and n = 22 cocaine).
