Table 1.

Proteins suggested as potential biomarkers for Sz or BPD due to diagnostic-specific changes detected using surface-enhanced laser desorption/ionization time of flight mass spectrometry in postmortem CNS.

Diagnoses	Proposed biomarker
Sz	CD58 molecule Calmodulin 1 (phosphorylase kinase, delta) Mago-nashi homolog, proliferation-associated (Drosophila) MYC associated factor X Regulator of G-protein signaling 11 Ubiquitin carboxyl-terminal hydroxylase isozyme L1 Cyclophilin A CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta LOC153154 similar to short heat shock protein 60 Hsp60s2 Phosphoglycerate mutase 1 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide NK2 homeobox 4, 2,4-dienoyl CoA reductase 2 Peroxisomal, methylthioadenosine phosphorylase Purine nucleoside phosphorylase Bystin-like Ankyrin repeat domain 12 Proteasome (prosome, macropain) subunit, alpha type, 7 Aldolase C, fructose-bisphosphate Sphingomyelin phosphodiesterase 1, acid lysosomal Glutamate-ammonia ligase and enolase 2 (gamma, neuronal)
BPD	Myelin basic protein Dickkopf homolog 2 (Xenopus laevis) CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta; 2,4-dienoyl CoA reductase 2, peroxisomal Bystin-like Ankyrin repeat domain 12 Aldolase C, fructose-bisphosphate