Table 1.
Results of neurologic examination, neurocognitive testing, and psychotropic medication load pre- and postelectrode implantation.
Electrode placement | Bilateral centromedian parafascicular complex (CM-Pf) | Preimplantation | Postimplantation |
---|---|---|---|
Neurologic testing | YGTSS Scoresa | Date of testing 12-22-2009 |
Date of testing 08-05-2010 |
| |||
Number motor | 2 | 1 | |
Number phonic | 1 | 0 | |
Frequency motor | 5 | 1 | |
Frequency phonic | 2 | 0 | |
Intensity motor | 5 | 2 | |
Intensity phonic | 2 | 0 | |
Complexity motor | 2 | 0 | |
Complexity phonic | 1 | 0 | |
Interference motor | 5 | 0 | |
Interference phonic | 2 | 0 | |
Overall impairment | 50 | 10 | |
Global severity | 77 | 14 | |
| |||
Neurocognitive testing | WAIS-III/IVb | Date of testing 12-23-2009 |
Date of testing 08-02-2010 |
| |||
Full scale IQ | 76 | 74 | |
Verbal comprehension | 84 | 78 | |
Perceptual organization | 76 | 73 | |
Working memory | 80 | 86 | |
Processing speed | 76 | 81 | |
| |||
Psychosocial testing | BASCc | Date of testing 12-23-2009 |
Date of testing 08-02-2010 |
| |||
Clinical scales | Hyperactivity | 68 | 59 |
Aggression | 52 | 45 | |
Conduct problems | 56 | 56 | |
Anxiety | 79 | 59 | |
Depression | 78 | 52 | |
Somatization | 69 | 54 | |
Atypicality | 69 | 49 | |
Withdrawal | 53 | 42 | |
Attention problems | 63 | 55 | |
| |||
Adaptive scales | Adaptability | 33 | 49 |
Social skills | 52 | 62 | |
Leadership | 40 | 53 | |
Activities daily living | 32 | 45 | |
Functional communication | 39 | 53 | |
| |||
Composite scales | Externalizing problems | 60 | 54 |
Internalizing problems | 81 | 56 | |
Behavioral symptoms index | 68 | 50 | |
Adaptive skills | 37 | 53 | |
| |||
Psychiatric evaluation | Psychotropic medicationsd | Date of evaluation 12-22-2009 |
Date of evaluation 08-05-2010 |
| |||
Aripiprazole 30 mg Diazepam 20 mg Divalproex sodium 3000 mg Guanfacine 2.5 mg Quetiapine 400 mg Risperidone 1.5 mg |
Risperidone 6 mg Guanfacine 2 mg |
aYGTSS:Yale Global Tic Severity Scale.
bWAIS-III/IV: Wechsler Adult Intelligence Scale-III/IV—Standard scores with a general population mean of 100 and a standard deviation of 15 are reported here. The WAIS III was administered preimplantation. The WAIS IV was administered postimplantation.
cBASC: Behavior Assessment System for Children, Second Edition Ages 12–21; raw test scores reported here. A score reduction on items within clinical scales reflects relative improvement in the different measures of psychiatric symptomatology, whereas a score increase on items within adaptive scales reflects a relative improvement on different measures of adaptive functioning. Within the composite scales, a score reduction in the domains of externalizing symptoms, internalizing symptoms, and behavioral symptoms reflects relative improvement, whereas a score increase in the adaptive skills domain reflects relative improvement.
dPsychotropic medications reported as maximum daily dosages prescribed to patient.