1 |
Female |
26 |
Asian |
Oral ulcers, Raynaud's, hemolytic anemia |
ANA, anti-Sm, anti-Sm/RNP |
Sparse interstitial neutrophilic dermatitis |
Prednisone 40 mg, hydroxychloroquine |
Responsive to treatment |
2 |
Female |
23 |
Asian |
Malar rash, pericarditis, arthritis, hemolytic anemia |
ANA, anti-dsDNA, anti-La, |
Neutrophilic dermatitis |
Prednisone |
Responsive to treatment |
3 |
Male |
23 |
Asian |
|
ANA, dsDNA |
Neutrophilic dermatitis |
Hydroxychloroquine, prednisone |
Responsive to treatment |
Goette 1985 [7] |
Male |
67 |
NA |
Arthritis, malar, and discoid rashes, leukopenia, thrombocytopenia |
ANA |
Prominent dermal edema, extensive infiltration with intact and karyorrhectic PMNs |
Prednisone 30–40 mg, quinacrine hydrochloride 100 mg |
Responsive to treatment |
Choi and Chung, 1999 [5] |
Female |
13 |
Asian |
Malar rash, oral ulcers, leukopenia, thrombocytopenia, nephritis |
ANA, anti-Sm, anti-dsDNA |
Neutrophilic dermatosis |
Pulse methylprednisolone |
Responsive to treatment |
Burnham and Cron, 2005 [10] |
Female |
14 |
African American |
Arthritis, oral ulcer, leukopenia |
ANA, anti-dsDNA, anti-Ro, anti-La, anti-SM/RNP |
Marked edema of papillary dermis with early subepidermal bullae, PMNs and karyorrhexis |
NA |
NA |
Hou et al., 2005 [8] |
Female |
38 |
Asian |
Arthritis, proteinuria >0.5 mg/day, |
ANA, anti-Ro, anti-La |
Neutrophilic dermatosis |
Prednisolone 20 mg |
Responsive to treatment |
Gleason et al., 2006 [9] |
Female |
16 |
NA |
Arthritis, serositis, leukopenia |
ANA, anti-dsDNA |
Neutrophilic dermatosis |
Hydroxychloroquine, prednisone |
Responsive to treatment |
Gleason et al., 2006 [9] |
Female |
35 |
NA |
Arthritis, hematuria (lupus nephritis on prior biopsy) |
ANA, anti-dsDNA, anti-Ro |
Neutrophilic dermatosis |
Corticosteroids, dapsone, azathioprine |
Responsive to treatment |
Camarillo et al., 2008 [3] |
Female |
9 |
NA |
Lymphopenia, (mesangial glomerulonephritis prior) |
ANA, anti-dsDNA, anti-RNP |
Interstitial dermal infiltrate of histiocytelike cells, lymphocytes and segmented neutrophils and leukocytoclastic debris |
Methylprednisolone, dapsone |
Responsive to treatment |
Fernandes et al., 2009 [6] |
Male |
25 |
NA |
Leukopenia, proteinuria, malar rash |
ANA, anti-Sm/RNP, anti-dsDNA |
Neutrophilic dermatitis |
Prednisone |
Responsive to treatment |
Gollol-Raju et al., 2009 [4] |
Female |
23 |
NA |
Malar rash (lupus nephritis previously) |
ANA |
Acute inflammatory cells with overlying keratin debris, abundant neutrophilic dust |
Corticosteroids |
Responsive to treatment |