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. 2011 Nov 14;2011:242681. doi: 10.1155/2011/242681

Table 1.

Demographic and clinical characteristics of SLE patients at time of presentation with Sweet's.

Patient Gender Age Race/ethnicity Clinical manifestations of SLE at time of Sweet's presentation Serologies Histopathology Treatment Response
1 Female 26 Asian Oral ulcers, Raynaud's, hemolytic anemia ANA, anti-Sm, anti-Sm/RNP Sparse interstitial neutrophilic dermatitis Prednisone 40 mg, hydroxychloroquine Responsive to treatment
2 Female 23 Asian Malar rash, pericarditis, arthritis, hemolytic anemia ANA, anti-dsDNA, anti-La, Neutrophilic dermatitis Prednisone Responsive to treatment
3 Male 23 Asian ANA, dsDNA Neutrophilic dermatitis Hydroxychloroquine, prednisone Responsive to treatment
Goette 1985 [7] Male 67 NA Arthritis, malar, and discoid rashes, leukopenia, thrombocytopenia ANA Prominent dermal edema, extensive infiltration with intact and karyorrhectic PMNs Prednisone 30–40 mg, quinacrine hydrochloride 100 mg Responsive to treatment
Choi and Chung, 1999 [5] Female 13 Asian Malar rash, oral ulcers, leukopenia, thrombocytopenia, nephritis ANA, anti-Sm, anti-dsDNA Neutrophilic dermatosis Pulse methylprednisolone Responsive to treatment
Burnham and Cron, 2005 [10] Female 14 African American Arthritis, oral ulcer, leukopenia ANA, anti-dsDNA, anti-Ro, anti-La, anti-SM/RNP Marked edema of papillary dermis with early subepidermal bullae, PMNs and karyorrhexis NA NA
Hou et al., 2005 [8] Female 38 Asian Arthritis, proteinuria >0.5 mg/day, ANA, anti-Ro, anti-La Neutrophilic dermatosis Prednisolone 20 mg Responsive to treatment
Gleason et al., 2006 [9] Female 16 NA Arthritis, serositis, leukopenia ANA, anti-dsDNA Neutrophilic dermatosis Hydroxychloroquine, prednisone Responsive to treatment
Gleason et al., 2006 [9] Female 35 NA Arthritis, hematuria (lupus nephritis on prior biopsy) ANA, anti-dsDNA, anti-Ro Neutrophilic dermatosis Corticosteroids, dapsone, azathioprine Responsive to treatment
Camarillo et al., 2008 [3] Female 9 NA Lymphopenia, (mesangial glomerulonephritis prior) ANA, anti-dsDNA, anti-RNP Interstitial dermal infiltrate of histiocytelike cells, lymphocytes and segmented neutrophils and leukocytoclastic debris Methylprednisolone, dapsone Responsive to treatment
Fernandes et al., 2009 [6] Male 25 NA Leukopenia, proteinuria, malar rash ANA, anti-Sm/RNP, anti-dsDNA Neutrophilic dermatitis Prednisone Responsive to treatment
Gollol-Raju et al., 2009 [4] Female 23 NA Malar rash (lupus nephritis previously) ANA Acute inflammatory cells with overlying keratin debris, abundant neutrophilic dust Corticosteroids Responsive to treatment