Table 2.

Inflammatory activity tests and serologic and autoantibodies tests.

	09/12/2007	10/30/2007	03/06/2008	07/02/2008
ESR (mm/h) RV: <20	67	54		55
CRP (mg/dL) RV: <0,5	<0,5	<0,5		<0,5
Total protein (g/dL) RV: 6–8		72
ANA RV: nonreactive	Nonreactive	Nonreactive	Nonreactive
RF (UI/mL) RV: <40	<40	<40	<40
P-ANCA RV: negative			1 : 20
Anti-TPO (UI/mL) RV: <35			842
Anti-TBG (UI/mL) RV: <40			141
Negative autoantibodies: anti-Scl70, anti-Jo1, c-ANCA, anti-RNP, anti-SS-A, anti-SS-B, anti-CCP, antinative DNA, and anticentromere.
Mycoplasma pneumoniae, Chlamydia pneumoniae, HBV and HCV negative serologic tests.

ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ANA: antinuclear antibodies; RF: rheumatoid factor; P-ANCA: perinuclear antineutrophil cytoplasmic antibodies; anti-TPO: antithyroid peroxidase; anti-TGB: antithyroxine binding globulin; anti-Scl 70: antitopoisomerase antibodies; anti-Jo 1: antisynthetase antibodies; c-ANCA: cytoplasmic antineutrophil cytoplasmic antibodies; anti-RNP: antiribonucleoproteins antitopoisomerase antibodies; anti-SS-A: anti-Sjogren's Syndrome antigen A; anti-SS-B: anti-Sjogren's syndrome antigen B; anti-CCP: anticitrulline containing peptide; HBV: hepatitis B virus; HCV: hepatitis C virus; RV: reference value.