Table 2. Characteristics of participants without antihypertensive treatment according to quartiles of natural log of PTH levels.
Natural log of PTH | |||||
<0.62 | 0.62–1.01 | 1.02–1.36 | >1.36 | ||
(n = 303) | (n = 302) | (n = 299) | (n = 302) | P | |
25(OH)D, ng/ml | 24.4±8.1 | 23.3±8.1 | 22.5±8.3 | 21.6±8.2 | 0.0002 |
PTH, pmol/l | 1.41 | 2.29 | 3.27 | 4.98 | – |
(1.11–1.63) | (2.05–2.50) | (3.00–3.52) | (4.35–6.09) | ||
Study outcomes | |||||
Systolic BP, mmHg | 121.2±15.6 | 122.3±17.3 | 125.6±19.0 | 128.0±20.6 | <0.0001 |
Diastolic BP, mmHg | 76.7±9.8 | 77.3±10.8 | 78.4±11.0 | 80.2±13.0 | 0.0006 |
Pulse pressure, mmHg | 44.5±10.0 | 44.9±10.1 | 47.2±12.2 | 47.8±12.1 | 0.0003 |
Possible confounders | |||||
Male, % | 57.4 | 57.0 | 63.6 | 63.6 | 0.16 |
Age, years | 43.3±12.4 | 45.6±11.4 | 48.7±13.0 | 50.4±12.0 | <0.0001 |
BMI, kg/m2 | 22.9±3.1 | 23.0±3.1 | 23.5±3.5 | 23.6±3.3 | 0.01 |
Total cholesterol, mmol/l | 5.4±1.1 | 5.4±1.1 | 5.4±1.0 | 5.5±1.1 | 0.85 |
Serum glucose, mmol/l | 5.2±1.7 | 5.2±1.6 | 5.3±1.3 | 5.6±2.3 | 0.03 |
GFR, ml/min.1.73 m2 | 97.2±18.1 | 96.7±18.3 | 95.8±19.5 | 94.6±21.0 | 0.37 |
Current alcohol intake, % | 22.4 | 23.8 | 22.7 | 25.5 | 0.81 |
Current smoking, % | 33.7 | 37.8 | 38.1 | 38.1 | 0.61 |
Hypertension, % | 15.2 | 19.5 | 25.8 | 30.1 | <0.0001 |
Data are mean ± standard deviation, or median (interquartile range), or percentages. BMI, body mass index; BP, blood pressure; GFR, glomerular filtration rate.