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. 2012 Aug 16;7(8):e43535. doi: 10.1371/journal.pone.0043535

Figure 2. Effects of cocaine withdrawal on anxiety-related behavior.

Figure 2

Behavior was assessed in the elevated plus-maze (A–C, n = 7–10), open arm (D–F, n = 10–14) and shock-probe burying tests (G–I, n = 10–14) in cocaine-treated rats (black bars) compared to saline-treated rats (white bars). Data are expressed as mean + SEM. *p<0.05, **p<0.01 versus saline-treated rats and # p<0.05 versus cocaine-treated rats at withdrawal day 2; Kruskal-Wallis test followed by a Mann-Whitney U test for pairwise comparisons.