Table 1. Densities of neurons and astroglial cells and proportion of Fos-positive cells expressing GAD mRNA or vGlut1 mRNA in the mPFC.
Infralimbic cortex | Prelimbic cortex | Anterior Cingulate cortex | ||||
Saline | Cocaine | Saline | Cocaine | Saline | Cocaine | |
NeuN | 2275.11±85.05 | 2376.12±120.38 | 2089.38±96.64 | 2218.24±72.7 | 1546.26±46.61 | 1927.91±50.18 |
GFAP | 722.19±77.75 | 646.03±62.91 | 607.13±77.89 | 668.25±134.46 | 496.23±60.23 | 509.4±32.74 |
% Fos-GAD | 35.46±4.42 | 28.32±2.59 | 31.05±3.20 | 25.22±2.81 | 35.26±8.58 | 36.52±6.51 |
% Fos-vGlut1 | 65.56±6.14 | 66.15±3.66 | 71.92±5.23 | 78.69±3.41 | 75.79±4.23 | 79.51±5.96 |
Quantification was performed in infralimbic, prelimbic and anterior cingulate cortices of cocaine- and saline-treated rats after open arm exposure. Data are expressed as mean ± SEM of three rats from each group and represent the density of labeled cells/mm2 or the percentage of Fos-expressing cells containing the mRNAs coding for vGlut1 or GAD.