Figure 7. Annotated 2D similarity plot for Lsr system LMNAST weak search hits.

A. HGT of homologous systems is evident among hits with perfect organizational homology but diminished mean element homology. A great number of hits have low similarity along both axes. As seen in B., these hits are mostly involved in the metabolism of 5 carbon carbohydrates according to their annotation. This is likely reflective of the fact that AI-2 is of similar structure to 5 carbon sugars.