Figure 1. Nora virus is targeted by RNAi in adult flies.

(A) Size distribution of Nora virus-derived small RNAs in libraries from thoraxes, bodies and heads of w¹¹¹⁸ flies. Read counts of small RNAs matching the (+) and (−) viral RNA strands are in gray and black, respectively. (B) Proportion of (+) Nora virus small RNA reads of total viral reads. Frequencies were computed from the distributions in panel A for each size class. (C) Viral siRNA distribution across the viral genome. The abundance of 21-nt small RNAs matching the (+) and (−) viral RNA strands of the reconstituted Nora virus (rNora) reference genome is shown in gray and black, respectively. (D) Z-scores for the number of overlapping pairs of sense and antisense 21-nt Nora virus small RNAs matching the rNora virus reference genome. For each possible overlap of 1 to 21-nt, the number of read pairs was counted and converted into a Z-score.