Transplant-free survival by endothelial nitric oxide synthase (NOS3) codon 298 polymorphism, GRACE study, University of Pittsburgh: Overall cohort (n=469): Asp298 variant (solid line, n=266), Glu298 homozygotes (dashed line, n=203). Event-free survival significantly poorer in subjects with the Asp298 variant, p=0.03 (reference 33)